Treatments for childhood Hodgkin lymphoma

If your child has Hodgkin lymphoma (HL), the healthcare team will create a treatment plan just for your child. It will be based on your child’s health and specific information about the cancer. When deciding which treatments to offer for childhood HL, the healthcare team will consider:

  • the type of HL
  • the stage of the cancer
  • the number of lymph node areas that have cancer
  • your child’s age
  • your child’s overall health

Childhood HL is generally treated using chemotherapy, with or without radiation therapy. Find out more about treatments for childhood classical HL and treatments for childhood nodular lymphocyte-predominant HL. Changes to the treatment plan may be made based on your child’s response to treatment.

Expert review and references

  • American Cancer Society. Treating Hodgkin Lymphoma in Children. 2018: https://www.cancer.org.
  • Lymphoma-Hodgkin-childhood. American Society of Clinical Oncology (ASCO). Cancer.Net. Alexandria, VA.: American Society of Clinical Oncology (ASCO); 2013.
  • B.C. Children's Hospital. Lymphoma. Vancouver, B.C.: B. C. Children's Hospital; 2003.
  • de Alarcon, Pedro A. Pediatric Hodgkin Lymphoma Treatment and Management. 2017: http://emedicine.medscape.com/.
  • Hendershot, E . Hodgkin's disease. Tomlinson, D. & Kline, N. E. Pediatric Oncology Nursing: Advanced Clinical Handbook. Germany: Springer; 2005: 2.1: pp.26-30.
  • Hudson, M. M., Mihaela, O. and Donaldson S. S . Hodgkin lymphoma. Pizzo, P. A. & Poplack, D. G. (Eds.). Principles and Practice of Pediatric Oncology. 5th ed. Philadelphia: Lippincott Williams & Wilkins; 2006: 23:695-719.
  • Liebhauser, P . Hodgkin's Disease. Baggott, C. R., Kelly, K. P., Fochtman, D. et al. Nursing Care of Children and Adolescents with Cancer. 3rd ed. Philadelphia, PA: W. B. Saunders Company; 2002: 22: pp. 524-535.
  • Hodgkin lymphoma in children. Macmillan Cancer Support. Macmillan Cancer Support. London, UK: Macmillan Cancer Support; 2012.
  • National Cancer Institute. Childhood Hodgkin Cancer Treatment (PDQ®) Patient Version. 2018.
  • National Cancer Institute. Childhood Hodgkin Lymphoma Treatment (PDQ®) Health Professional Version. 2018: http://www.cancer.gov/.
  • Hodgkin lymphoma. National Childhood Cancer Foundation & Children's Oncology Group. CureSearch. Bethesda, MD: 2011.

Treatments for childhood classical Hodgkin lymphoma

Treatments for childhood classic Hodgkin lymphoma include chemotherapy and radiation therapy. Learn more about treatment options.

Treatments for childhood nodular lymphocyte-predominant Hodgkin lymphoma

Treatments for childhood nodular lymphocyte-predominant Hodgkin lymphoma are surgery, chemotherapy and radiation. Learn more about treatment options.

Treatments for recurrent or refractory childhood HL

Treatments of primary progressive or recurrent childhood Hodgkin lymphoma include chemotherapy, radiation and stem cell transplant. Learn more.

Chemotherapy for childhood Hodgkin lymphoma

Chemotherapy is commonly used to treat childhood Hodgkin lymphoma. Learn when chemotherapy is used and what chemotherapy drugs and combinations are used.

Radiation therapy for childhood Hodgkin lymphoma

Radiation therapy is often used to treat childhood Hodgkin lymphoma. Learn about radiation therapy, when it is used and how it is given.

Stem cell transplant for childhood Hodgkin lymphoma

Stem cell transplant may be used to treat childhood Hodgkin lymphoma that doesn’t respond to treatment or recurs after treatment. Learn more.

Targeted therapy for childhood Hodgkin lymphoma

Targeted therapy is sometimes used to treat certain types of childhood Hodgkin lymphoma (HL). It uses drugs to target specific molecules (such as proteins) on or inside cancer cells. These molecules help send signals that tell cells to grow or divide. By targeting these molecules, the drugs stop the growth and spread of cancer cells and limit harm to normal cells. Targeted therapy may also be called molecular targeted therapy.

Follow-up after treatment for childhood Hodgkin lymphoma

Follow-up after childhood Hodgkin lymphoma treatment varies. Learn about scheduled follow-up appointments and the procedures and tests that may be done.

Late effects of treatments for childhood Hodgkin lymphoma

Adjusting to life after treatment for childhood Hodgkin lymphoma is different for each child. Learn how to cope with the late side effects of treatment.