Treatments for stage 0 penile cancer
The following are treatment options for stage 0 penile cancer. Stage 0 penile carcinoma may also be called carcinoma in situ (CIS) or verrucous carcinoma. CIS on the head (glans) of the penis may be called erythroplasia of Queyrat. CIS on the shaft of the penis may be called Bowen’s disease. Your healthcare team will suggest treatments based on your needs and work with you to develop a treatment plan.
Surgery is the main treatment for stage 0 penile cancer. It is often the only treatment needed for most early stage penile cancers.
Circumcision removes the foreskin of the penis. It may be used for penile cancer that is only on the foreskin.
Mohs surgery removes the cancer in layers, little by little, until no cancer remains.
Glansectomy removes the head (glans) of the penis.
Wide local excision removes the tumour along with a margin of normal tissue around it.
Laser surgery uses an intense, narrow beam of light (called a laser beam) to destroy cancer cells.
Cryosurgery uses extreme cold to freeze and destroy tissue.
Drug therapy @(Model.HeadingTag)>
You may be offered topical therapy for stage 0 penile cancer. A cream or gel is applied directly to the abnormal area on the penis. The most common topical therapy drugs used are:
- 5-fluorouracil (Efudex, 5-FU)
- imiquimod (Aldara)
Clinical trials @(Model.HeadingTag)>
Alberta Health Services. Penile Cancer Clinical Practice Guideline GU-006. Alberta Health Services; 2012: http://www.albertahealthservices.ca/.
American Cancer Society. Treating Penile Cancer. 2018: https://www.cancer.org/.
BC Cancer Agency. Penis. BC Cancer Agency; 2015: http://www.bccancer.bc.ca/.
Brosman, SA. Medscape Reference: Penile Cancer. 2015: http://emedicine.medscape.com/article/446554-overview.
Cancer Research UK. Treatment Options for Penile Cancer. 2021: https://www.cancerresearchuk.org/.
PDQ Adult Treatment Editorial Board. Penile Cancer Treatment (PDQ®) – Health Professional Version. Bethesda, MD: National Cancer Institute; 2023: https://www.cancer.gov/.
National Comprehensive Cancer Network . NCCN Clinical Practice Guidelines in Oncology: Penile Cancer (Version 1.2023). 2022.
Richter S, Ruether JD, Wood L, Canil C, Moretto P, et al . Management of carcinoma of the penis: consensus statement from the Canadian Association of Genitourinary Medical Oncologists (CAGMO). Canadian Urological Association Journal. 2013.
Van Poppel H, Watkin NA, Osanto S, Moonen L, Horwich A, Kataja V.. Penile cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Annals of Oncology. 2013: 24(Supplementary 6): VI115–VI124.