Treatments for cancer of unknown primary
If you have cancer of unknown primary (CUP), your healthcare team will create a treatment plan just for you. It will be based on your needs and may include a combination of different treatments. When deciding which treatments to offer for CUP, your healthcare team will consider:
- the type of CUP
- the amount of differentiation of the cancer cells
- whether it is favourable-risk or poor-risk CUP
- where and how many different places cancer is found
- where the cancer may have started (called the primary site)
- your overall health
- your age
- your preferences for treatment
Fizazi K, Greco FA, Pavlidis N, et al . Cancers of unknown primary site: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Annals of Oncology. Oxford University Press; 2011.
Greco FA & Hainsworth JD . Cancer of unknown primary site. DeVita VT Jr, Lawrence TS, & Rosenberg SA. Cancer: Principles & Practice of Oncology. 10th ed. Philadelphia: Wolters Kluwer Health/Lippincott Williams & Wilkins; 2015: 113:1720-1737.
Kim KW, Krajewski, KM, Jagannathan JP, et al . Cancer of unknown primary sites: what radiologists need to know and what oncologists want to know. AJR: American Journal of Roentgenology. The American Roentgen Ray Society; 2013.
National Comprehensive Cancer Network. Occult Primary (Cancer of Unknown Primary [CUP]) (Version 3.2014). http://www.nccn.org/professionals/physician_gls/pdf/occult.pdf.
Stella GM, Senetta R, Cassenti A, Ronco M, & Cassoni P . Cancers of unknown primary origin: current perspectives and future therapeutic strategies. Journal of Translational Medicine. 2012: http://www.translational-medicine.com/content/10/1/12.