Survival statistics for brain and spinal cord tumours

Survival statistics for brain and spinal cord tumours are very general estimates and must be interpreted very carefully. Because these statistics are based on the experience of groups of people, they cannot be used to predict a particular person’s chances of survival.

There are many different ways to measure and report cancer survival statistics. Your doctor can explain the statistics for brain and spinal cord tumours and what they mean to you.

Statistics are not always available for all types of brain and spinal cord tumours, often because they are rare or hard to classify.

Net survival

Net survival represents the probability of surviving cancer in the absence of other causes of death. It is used to give an estimate of the percentage of people who will survive their cancer.

In Canada, the 5-year net survival for all brain and central nervous system tumours is 22%. This means that about 22% of people diagnosed with brain and central nervous system tumours will survive at least 5 years.

Survival by prognostic factors

Survival varies with each grade and particular type or subtype of brain and spinal cord tumour. The following factors can also affect survival for brain and spinal cord tumours. However, survival rates for brain tumours will vary widely, depending on the type of tumour, its grade and the location in the brain.

  • Low-grade tumours have a more favourable prognosis than high-grade tumours.
  • People younger than 65 years of age have a more favourable prognosis.
  • People with a better performance status and neurological status have a more favourable prognosis.
  • Tumours that can be surgically removed have a more favourable prognosis than tumours that can be partially removed or not removed. Tumours that are in parts of the brain where they cannot be easily removed by surgery have lower survival rates.

Survival statistics for gliomas

Brain and spinal cord tumour survival may be reported as:

  • Relative survival, which compares the survival for a group of people with cancer to the survival expected for a group of people in the general population who share the same characteristics as the people with cancer (such as age, sex and place of residence). Ideally, the group of people used in the general population would not include people with cancer, but this estimate can be difficult to obtain. As a result, relative survival can sometimes be overestimated.
  • Median survival, which is the period of time (usually months or years) at which half of the people with a tumour are still alive. The other half will live less than this amount of time.

The numbers given below are the most current statistics available. However, they represent people who were diagnosed and treated many years ago. Improvements in treatment since then means that for people being diagnosed now, the survival rates may be higher.

Astrocytoma (1973-2004)

Type of tumour

Age

5-year relative survival

Median survival

pilocytic astrocytoma

( grade 1)

& #160;

greater than 90%

& #160;

diffuse astrocytoma

( grade 2)

20–44

57%

5–7 years

45–54

37%

55–64

10%

anaplastic astrocytoma

( grade 3)

20–44

48%

2–3 years

45–54

25%

55–64

5%

glioblastoma multiforme

( grade 4)

20–44

14%

12–14 months

45–54

4%

55–64

1%
Oligodendroglioma (1973-2004)

Type of tumour

Age

5-year relative survival

oligodendroglioma

( grade 2)

20–44

82%

45–54

67%

55–64

48%

anaplastic oligodendroglioma

( grade 3)

20–44

64%

45–54

50%

55–64

23%
Ependymoma (1973-2004)

Type of tumour

Age

5-year relative survival

ependymoma (grade 1 and 2) and

anaplastic ependymoma (grade 3)

20–44

86%

45–54

80%

55–64

69%

Survival rates for those 65 or older are usually lower.

Survival statistics for other brain and spinal cord tumours

Meningioma

Meningioma (grade 1) – About 80% of people remain progression-free 10 years.

Atypical meningioma (grade 2) – About 35% of people remain progression-free 10 years.

Anaplastic or malignant meningioma (grade 3) – These tumours have a median survival of less than 2 years.

Primary central nervous system lymphoma (PCNSL)

The median progression-free survival is approximately 12.8 months with chemotherapy alone and up to 5 years with combination chemotherapy and radiation therapy.

Brain metastases and spinal cord metastases

Median survival ranges from 7–24 weeks.

Survival varies depending on the site of the primary tumour.

Questions about survival

People with cancer should talk to their doctor about their prognosis. Prognosis depends on many factors, including:

  • your health history
  • type of cancer
  • stage
  • characteristics of the cancer
  • treatments chosen
  • how the cancer responds to treatment

Only a doctor familiar with these factors can put all of this information together with survival statistics to arrive at a prognosis.

Expert review and references

  • American Cancer Society. Brain and Spinal Cord Tumors in Adults. Atlanta, GA: American Cancer Society; 2010.
  • Armstrong T. Central nervous system cancer. Yarbro, CH, Wujcki D, & Holmes Gobel B. (eds.). Cancer Nursing: Principles and Practice. 7th ed. Sudbury, MA: Jones and Bartlett; 2011: 49: pp. 1146-1187.
  • Barnholtz-Sloan JS, Sloan AE, & Schwartz AG. Cancer of the brain and other central nervous system. National Cancer Institute. Surveillance Epidemiology and End Results (SEER). Bethesda, MD: National Cancer Institute;
  • Canadian Cancer Statistics Advisory Committee. Canadian Cancer Statistics 2019. Toronto, ON: Canadian Cancer Society; 2019. https://cancer.ca/en/research/cancer-statistics/past-editions.
  • Minniti G, Brada M, Kleihues P et al. Gliomas. Gospodarowicz, M. K., O'Sullivan, B., Sobin, L. H., et al. (Eds.). Prognostic Factors in Cancer. 3rd ed. Hoboken, NJ: John Wiley & Sons, Inc.; 2006: 44: pp. 307-310.
  • National Cancer Institute. Adult Brain Tumors Treatment (PDQ®) Health Professional Version. Bethesda, MD: National Cancer Institute; 2010.
  • Preston-Martin S, Munir R, & Chakrabarti, I. Nervous system. Schottenfeld, D. & Fraumeni, J. F. Jr. (eds.). Cancer Epidemiology and Prevention. 3rd ed. New York: Oxford University Press; 2006: 4.62: pp. 1173-1195.
  • Canadian Cancer Statistics Advisory Committee. Canadian Cancer Statistics 2021. Canadian Cancer Society; 2021.

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