Follow-up after treatment for childhood bone cancer

Last medical review:

Follow-up after treatment is an important part of cancer care. Follow-up for childhood bone cancer is often shared by a team of healthcare professionals such as cancer doctors, audiologists, speech-language pathologists, dentists, eye doctors, nurses and psychologists. This team will work with you to decide on follow-up care to meet your child's needs.

Follow-up is important because there is a chance the cancer can come back (recur) and late side effects from treatment can develop. Initial follow-up focuses on checking to see if cancer has come back and making sure that the child has recovered from treatment. If your child has any new symptoms or symptoms that don't go way, don't wait until the next scheduled appointment to report them. Tell the healthcare team if your child has:

  • pain
  • swelling or a lump

Schedule for follow-up visits

The healthcare team will follow all children treated for bone cancer to make sure they are growing and developing normally. The chance of childhood bone cancer recurring is greatest within 18 months of completing treatment for osteosarcoma and within 2 years of completing treatment for Ewing sarcoma. Close follow-up is usually done for the first 5 years after completing treatment.

Children who have limb-sparing surgery need careful orthopedic follow-up. They will also need to see a rehabilitation medicine specialist, physiotherapist and occupational therapist.

Children who have limb-sparing surgery or amputation often need lifelong follow-up with an orthopedic surgeon.

Follow-up visits with the healthcare team are usually scheduled:

  • every 3 months for the first 2 years after treatment
  • every 6 months for the next 3 years
  • every year for the next 5 years
  • every 2 to 3 years once 10 years have passed since treatment

During follow-up visits

During a follow-up visit, the healthcare team will usually ask questions about the side effects of treatment and how the child is coping. The doctor may do a complete physical exam, including:

  • feeling the lymph nodes
  • examining the area where the primary tumour was
  • checking that the child is growing normally
  • checking that the child's sexual development is normal

Tests are often part of follow-up care. Your child may have:

  • blood tests to check organ function
  • bone scan
  • a CT scan or MRI of the primary tumour site
  • an x-ray or a CT scan of the chest
  • an echocardiogram to check heart function

Children who have limb-sparing surgery need to have yearly x-rays to check:

  • if limbs are different lengths

  • grafts or implants to find out if they are healing properly or not (called non-union)
  • grafts for breaks, or fractures
  • implants to make sure they are not loose (a loose implant is called stem loosening)

If a recurrence or other problems are found during follow-up visits, the healthcare team will assess your child to determine the best treatment options. Some children may be referred to an endocrinologist if there are any problems with their sexual development.

Watching for late effects

In the long term, follow-up focuses on watching for late effects. People who had a childhood cancer may be followed in aftercare programs for life.

The Children's Oncology Group (COG) provides long-term follow-up guidelines for childhood cancer survivors. Some centres across Canada have transition clinics set up to follow the survivors of childhood cancer. These clinics help prepare survivors who are reaching early adulthood to successfully manage their own healthcare. Find out more about long-term survivorship.

Questions to ask about follow-up

Find out more about the Children’s Oncology Group long-term follow-up guidelines. To make the decisions that are right for your child, ask your child’s healthcare team questions about follow-up.

Expert review and references

  • Abha Gupta, MD, MSc, FRCPC
  • Raveena Ramphal, MBChB, FRACP

Medical disclaimer

The information that the Canadian Cancer Society provides does not replace your relationship with your doctor. The information is for your general use, so be sure to talk to a qualified healthcare professional before making medical decisions or if you have questions about your health.

We do our best to make sure that the information we provide is accurate and reliable but cannot guarantee that it is error-free or complete.

The Canadian Cancer Society is not responsible for the quality of the information or services provided by other organizations and mentioned on cancer.ca, nor do we endorse any service, product, treatment or therapy.


1-888-939-3333 | cancer.ca | © 2024 Canadian Cancer Society