Risks for thymus cancer

Last medical review:

Some things can affect your risk, or chance, of developing cancer. Certain behaviours, substances or conditions can increase or decrease the risk. Most cancers are the result of many risks. But sometimes cancer develops in people who don't have any risks.

There are no known risks for thymus cancer.

Thymus cancer is rare. It mostly occurs in people aged 40 or older. Thymus cancer seems to happen more often in people of Asian, Pacific Island and African ancestry.

Possible risks

Thymoma is the most common cancerous tumour of the thymus. The following have been linked with an increased risk of thymoma, but more research is needed to know for sure that they are risks:

  • Myasthenia gravis is an autoimmune disease that causes muscle weakness. The body's immune system makes antibodies that block or change some of the nerve signals to your muscles, making them weak.
  • Pure red cell aplasia is a rare blood disorder in which the bone marrow doesn’t make enough red blood cells, causing anemia.
  • Hypogammaglobulinemia is a condition in which there are not enough gamma globulins in the blood, which normally fight infections. So most people with hypogammaglobulinemia have recurrent infections.

Understanding your cancer risk

To make the decisions that are right for you, ask your doctor questions about risks. Learn how cancer can be prevented and what you can do to reduce your risk.

Expert review and references

  • Canadian Cancer Society | Société canadienne du cancer
  • American Cancer Society. What are the Risk Factors for Thymus Cancer?. 2024. https://www.cancer.org/.
  • Cameron RB, Girard N, Lee PP. Neoplasms of the mediastinum. DeVita VT Jr, Lawrence TS, Rosenberg S. eds. DeVita Hellman and Rosenberg's Cancer: Principles and Practice of Oncology. 12th ed. Philadelphia, PA: Wolters Kluwer; 2023: Kindle version, [chapter 32], https://read.amazon.ca/?asin=B0BG3DPT4Q&language=en-CA.
  • Cancer Research UK. Thymus Gland Cancer. 2022. https://www.cancerresearchuk.org/.
  • Engels EA. Epidemiology of thymoma and associated malignancies. Journal of Thoracic Oncology. 2010. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2951303/.
  • Macmillan Cancer Support. Thymus Cancer. 2023. https://www.macmillan.org.uk/.
  • OncoLink. Thymus Cancer (Thymoma and Thymic Carcinoma): The Basics . Trustees of the University of Pennsylvania; 2024. https://www.oncolink.org/.
  • PDQ Adult Treatment Editorial Board. Thymoma and Thymic Carcinoma Treatment (PDQ®) – Health Professional Version. Bethesda, MD: National Cancer Institute; 2024. https://www.cancer.gov/.
  • PDQ Adult Treatment Editorial Board. Thymoma and Thymic Carcinoma Treatment (PDQ®) – Patient Version. Bethesda, MD: National Cancer Institute; 2023. https://www.cancer.gov/.

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