Treatments for stage 1 soft tissue sarcoma

Last medical review:

The following are treatment options for stage 1 (localized and low-grade) soft tissue sarcoma. Your healthcare team will suggest treatments based on your needs and work with you to develop a treatment plan.

Surgery

Surgery is the main treatment for stage 1 soft tissue sarcoma. It’s often the only treatment needed.

The main goal of surgery is to remove the whole tumour along with some normal tissue around it (called the surgical margin). A wide excision is done to remove the tumour and a small amount of the surgical margin. Doctors may use other terms for wide excision, such as en bloc resection or wide resection.

Limb-sparing surgery is often used to remove tumours in an arm or a leg. During limb-sparing surgery, surgeons do a wide excision to remove the tumour without amputating the limb.

Sometimes another surgery is done to remove more tissue if cancer cells are found around the tumour (called a positive surgical margin), or if there wasn’t enough normal tissue removed.

Find out more about surgery for soft tissue sarcoma.

Radiation therapy

Radiation therapy uses high-energy rays or particles to destroy cancer cells.

You may be offered external radiation therapy for stage 1 soft tissue sarcoma. It may be given before surgery to reduce the risk of recurrence.

Sometimes, radiation therapy may be given after surgery if there are still cancer cells found around the tumour (called a positive surgical margin).

Find out more about radiation therapy for soft tissue sarcoma.

Clinical trials

Talk to your doctor about clinical trials open to people with soft tissue sarcoma in Canada. Clinical trials look at new ways to prevent, find and treat cancer. Find out more about clinical trials.

Expert review and references

  • Michael Monument, MD, MSc, FRCSC
  • Gronchi A, Miah AB, Dei Tos AP, et al.. Soft tissue and visceral sarcomas: ESMO–EURACAN–GENTURIS Clinical Practice Guidelines for diagnosis, treatment and follow-up. Annals of Oncology. 2021: 32(11):1348–1365.
  • National Comprehensive Cancer Network. NCCN Clinical Practice Guidelines in Oncology: Soft Tissue Sarcoma Version 1.2025 . 2025:
  • Samuel LC. Bone and soft tissue sarcomas. Yarbro CH, Wujcik D, Gobel B (eds.). Cancer Nursing: Principles and Practice. 8th ed. Burlington, MA: Jone & Bartlett Learning; 2018: Kindle version, chapter 46, https://read.amazon.ca/?asin=B01M6ZZEWT&ref_=kwl_kr_iv_rec_1.
  • PDQ Adult Treatment Editorial Board. Soft Tissue Sarcoma Treatment (PDQ®) – Health Professional Version . Bethesda, MD: National Cancer Institute; https://www.cancer.gov/.
  • Singer S, Tap WD, Kirsch DG, Agaram NP, D'Angelo SP, Crago AM. Soft Tissue Sarcoma. DeVita VT Jr, Lawrence TS, Rosenberg S. eds. DeVita Hellman and Rosenberg's Cancer: Principles and Practice of Oncology . 12th ed. Philadelphia, PA: Wolters Kluwer; 2023: Kindle version, [chapter 60], https://read.amazon.ca/?asin=B0BG3DPT4Q&language=en-CA.

Your trusted source for accurate cancer information

With support from readers like you, we can continue to provide the highest quality cancer information for over 100 types of cancer.

We’re here to ensure easy access to accurate cancer information for you and the millions of people who visit this website every year. But we can’t do it alone.

Every donation helps fund reliable cancer information, compassionate support services and the most promising research. Please give today because every contribution counts. Thank you.

Medical disclaimer

The information that the Canadian Cancer Society provides does not replace your relationship with your doctor. The information is for your general use, so be sure to talk to a qualified healthcare professional before making medical decisions or if you have questions about your health.

We do our best to make sure that the information we provide is accurate and reliable but cannot guarantee that it is error-free or complete.

The Canadian Cancer Society is not responsible for the quality of the information or services provided by other organizations and mentioned on cancer.ca, nor do we endorse any service, product, treatment or therapy.


1-888-939-3333 | cancer.ca | © 2026 Canadian Cancer Society