Types of mesothelioma

Last medical review:

Mesothelioma is a rare cancerous (malignant) tumour. It starts in the mesothelium and can grow into and destroy nearby tissue. It can also spread (metastasize) to other parts of the body.

Mesothelioma has different names depending on where it is in the body.

Pleural mesothelioma

Pleural mesothelioma is the most common type of mesothelioma. It starts in the pleura. The pleura is a membrane that lines the inside of the chest wall and covers each lung.

More men than women are diagnosed with pleural mesothelioma. We need more research and can’t say at this time what the incidence is for transgender, non-binary and gender-diverse people.

Peritoneal mesothelioma

Peritoneal mesothelioma is the second most common type of mesothelioma. It starts in the peritoneum. The peritoneum is the membrane that lines the inside of the abdomen and pelvis, and it surrounds many of the organs in these parts of the body.

Men and women are equally affected by peritoneal mesothelioma. We need more research and can’t say at this time what the incidence is for transgender, non-binary and gender-diverse people.

Very rare types of mesotheliomas

The following cancerous tumours of the mesothelium are very rare.

Pericardial mesothelioma starts in the membrane that surrounds the heart (called the pericardium). Treatment may include surgery, radiation therapy or chemotherapy.

Mesothelioma of the tunica vaginalis starts in the membrane that surrounds each testicle. Treatment is surgery to remove the testicle and the scrotum, as well as the lymph nodes in the area. Radiation therapy may be offered after surgery.

Expert review and references

  • John Cho, MD, PhD, FRCPC
  • American Cancer Society. Malignant Mesothelioma. 2018. https://www.cancer.org/.
  • Pass H, Carbone M, Tsao A, Rosenzweig Z. Benign and Malignant Mesothelioma. DeVita VT Jr, Lawrence TS, Rosenberg S. eds. DeVita Hellman and Rosenberg's Cancer: Principles and Practice of Oncology. 12th ed. Philadelphia, PA: Wolters Kluwer; 2023: Kindle version, [chapter 76], https://read.amazon.ca/?asin=B0BG3DPT4Q&language=en-CA.
  • National Comprehensive Cancer Network. NCCN Guidelines for Patients: Pleural Mesothelioma. 2022.
  • Nowak AK, Edwards JG, Creaney J. Mesothelioma. Raghavan D, Ahluwalia MS, Blanke CD, et al, eds.. Textbook of Uncommon Cancer. 5th ed. Hoboken, NJ: Wiley Blackwell; 2017: Kindle version (chapter 16) https://read.amazon.ca/?asin=B06XKD44V3&_encoding=UTF8&ref=dbs_p_ebk_r00_pbcb_rnvc00.
  • Sauter JL, Dacic S, Galateau-Salle F, et al. The 2021 WHO Classification of Tumors of the Pleura: Advances Since the 2015 Classification. Journal of Thoracic Oncology. 2022: 17(5):608–622.

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