What is liver cancer?
Cells in the liver sometimes change and no longer grow or behave normally. These changes may lead to non-cancerous (benign) tumours such as hemangiomas.
But in some cases, changes to liver cells can cause liver cancer. Most often, liver cancer starts in the cells that make up the body of the liver (called hepatocytes). This type of cancer is called hepatocellular carcinoma. It is the most common type of primary liver cancer.
Liver cancer can also start in the cells that line the bile ducts in the liver. This type of cancer is called intrahepatic bile duct cancer or cholangiocarcinoma. Find out more about intrahepatic bile duct cancer.
Other types of cancer can spread to the liver, but this is not the same disease as primary liver cancer. Cancer that starts in another part of the body and spreads to the liver is called liver metastasis. It is not treated in the same way as primary liver cancer. Find out more about liver metastases.
Bartlett DI, Di Bisceglie AM, & Dawson LA . Cancer of the liver. Devita, V. T., Jr., Lawrence, T. S., & Rosenberg, S. A. Cancer: Principles & Practice of Oncology. 8th ed. Philadelphia: Wolters Kluwer Health/Lippincott Williams & Wilkins; 2008: 39.7:pp. 1129-1156.
Grenon NN . Liver cancer. Yarbro, CH, Wujcki D, & Holmes Gobel B. (eds.). Cancer Nursing: Principles and Practice. 7th ed. Sudbury, MA: Jones and Bartlett; 2011: 58: pp. 1399-1423.
Martini FH, Timmons MJ, Tallitsch RB. Human Anatomy. 7th ed. San Francisco: Pearson Benjamin Cummings; 2012.
Venook AP, Poon RTP, Wong D, & Lawrence T . Hepatocellular cancer: clinical management. Kelsen, D. P., Daly, J. M., Kern, S. E., Levin, B., Tepper, J. E., & Van Cutsem, E. (eds.). Principles and Practice of Gastrointestinal Oncology. 2nd ed. Philadelphia: Lippincott Williams & Wilkins; 2008: 33: pp. 437-62.