What is gestational trophoblastic disease?
In rare cases, a pregnancy does not progress normally and may form a hydatidiform mole (molar pregnancy). These pregnancies lack an embryo and have abnormal growth of trophoblastic tissue. The body can abort hydatidiform moles completely (spontaneous abortion or miscarriage). If they do not abort completely, the woman will need a procedure to completely remove the abnormal tissue from the uterus.
GTD can occur:
- during a pregnancy
- after a miscarriage or surgical removal of a pregnancy (abortion)
- after a tubal pregnancy (implantation of the fertilized egg within the fallopian tube)
- after a normal pregnancy
American Cancer Society. Gestational Trophoblastic Disease. 2014: http://www.cancer.org/acs/groups/cid/documents/webcontent/003104-pdf.pdf.
American Society of Clinical Oncology. Gestational Trophoblastic Disease. 2014: http://www.cancer.net/cancer-types/gestational-trophoblastic-disease/view-all.
Goldstein DP, Berkowitz RS, Horowitz NS . Gestational trophoblastic diseases. DeVita VT Jr, Lawrence TS, Rosenberg SA. Cancer: Principles and Practice of Oncology. 10th ed. Philadelphia: Wolters Kluwer Health/Lippincott Williams & Wilkins; 2015: 75: 1069-1074.
Martini FH, Timmons MJ, Tallitsch RB. Human Anatomy. 7th ed. San Francisco: Pearson Benjamin Cummings; 2012.