Treatments for stage 3 cervical cancer

The following are treatment options for stage 3 cervical cancer. Your healthcare team will suggest treatments based on your needs and work with you to develop a treatment plan.

Chemoradiation

Chemoradiation is a main treatment for stage 3 cervical cancer. Chemotherapy is given during the same time period as radiation therapy to make the radiation therapy more effective.

Cisplatin or cisplatin plus 5-fluorouracil (Adrucil, 5-FU) is the chemotherapy that is used. If cisplatin is used, it is usually given one time each week during the radiation therapy schedule. If cisplatin plus 5-FU is used, it is usually given every 4 weeks during radiation therapy.

Brachytherapy (a type of internal radiation therapy) is usually given during and after external radiation therapy.

Radiation therapy

You may be offered radiation therapy for stage 3 cervical cancer. Women who have radiation therapy will have both external radiation therapy and brachytherapy. In most cases radiation therapy is given with chemotherapy (chemoradiation), but in some cases it may be used alone as the main treatment for stage 3 cervical cancer.

Clinical trials

Talk to your doctor about clinical trials open to women with cervical cancer in Canada. Clinical trials look at new ways to prevent, find and treat cancer. Find out more about clinical trials.

Expert review and references

  • Guideline Resource Unit (GURU). Cancer of the Uterine Cervix. Edmonton: Alberta Health Services; 2021: Clinical Practice Guideline GYNE-004 Version: 6. https://www.albertahealthservices.ca/info/cancerguidelines.aspx.
  • Chuang LT, Temin S, Berek JS. Management and care of patients with invasive cervical cancer: ASCO Resource-Stratified Guideline Rapid Recommendation Update. JCP Global Oncology. 8:1-4.
  • Cibula D, Raspollini MR, Planchamp F, Centeno C, Chargari C, et al. ESGO/ESTRO/ESP Guidelines for the management of patients with cervical cancer – Update 2023. International Journal of Gynecological Cancer. 2023: 33:649-666.
  • National Comprehensive Cancer Network. NCCN Clinical Practice Guidelines in Oncology: Cervical Cancer Version 1.2023. 2023.
  • PDQ Adult Treatment Editorial Board. Cervical Cancer Treatment] (PDQ®) – Health Professional Version. Bethesda, MD: National Cancer Institute; 2023. https://www.cancer.gov/.

Medical disclaimer

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