Symptoms of neuroendocrine tumours (NETs)
Neuroendocrine tumours (NETs) may not cause any signs or symptoms if they grow slowly and don’t make too much of a certain hormone. Signs and symptoms may appear as the tumour grows or if hormones are released by the tumour (if it is a functional tumour). Other health conditions can cause the same symptoms as NETs.
The signs or symptoms of NETs vary depending on where the tumour develops in the body.
Symptoms of gastrointestinal neuroendocrine tumours (GI NETs) @(Model.HeadingTag)>
Gastrointestinal neuroendocrine tumours (GI NETs) can develop in any part of the gastrointestinal tract, including the small or large intestine and stomach. Signs or symptoms of GI NETs may include:
- discomfort or pain in the abdomen or rectum
- nausea and vomiting
- bleeding from the rectum or blood in the stool
- anemia – may cause fatigue
- heartburn or indigestion
- stomach ulcers – can cause heartburn, indigestion and pain in the chest or abdomen
- weight loss
- blockage in the intestine (bowel obstruction) – may cause pain in the abdomen or constipation
Carcinoid syndrome is a group of symptoms caused by a NET releasing large amounts of
- flushing of the skin, mainly the face and neck
- wheezing and difficulty breathing
- fast or irregular heartbeat
- low blood pressure
- heart damage (carcinoid heart disease)
Carcinoid crisis is a severe case of flushing, low blood pressure, difficulty breathing and an irregular heartbeat. It may be triggered by anesthesia, surgery or other treatments. Carcinoid crisis is a serious and possibly life-threatening problem that needs to be treated right away. A drug called octreotide (Sandostatin) can be given to treat and reduce the risk of carcinoid crisis.
Symptoms of lung neuroendocrine tumours (lung NETs) @(Model.HeadingTag)>
Lung neuroendocrine tumours (lung NETs) usually develop in the airways (bronchi). Signs or symptoms of lung NETs may include:
- a cough that doesn’t go away
- coughing up blood
- difficulty breathing
- carcinoid syndrome – may include flushing of the skin, diarrhea and wheezing
Cushing syndrome is a group of symptoms caused by too much
- weight gain
- a red, round and full face
- muscle weakness
- increased hair growth on the face and body
- a buildup of fat between the shoulders or above the collar bone
- purple lines on the skin
- high blood pressure
- high blood sugar (glucose) levels
- changes in mood and behaviour
Symptoms of pancreatic neuroendocrine tumours (pNETs) @(Model.HeadingTag)>
Signs or symptoms of pancreatic neuroendocrine tumours (pNETs) depend mainly on the type of hormone released by the tumour. The signs or symptoms of pNETs include:
- low blood sugar levels (hypoglycemia) – may cause sweating, shakiness, dizziness, extreme hunger and problems concentrating
- high blood sugar levels (hyperglycemia) – may cause extreme thirst and frequent urination, diarrhea and fatty stools
- stomach ulcers – may cause heartburn, indigestion and pain in the chest or abdomen
- weight loss
- patches of red, itchy and painful skin
- blood clots
- Cushing syndrome – may include a red, round and full face
Zollinger-Ellison syndrome is a condition caused by too much
- pain in the abdomen
- severe diarrhea
- nausea and vomiting, sometimes vomiting blood
- weight loss
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