A procedure that uses a special machine (pheresis machine) to separate and collect platelets (blood cells that cause clotting) from withdrawn blood. The remaining blood is then returned to the body.

Plateletpheresis is used to lower a very high platelet count in people with thrombocytosis (an increase in platelets). It can also be used to collect donated platelets to treat people with a low platelet count or a clotting disorder.

Also called thrombopheresis or thrombocytopheresis.

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