Treatments for pituitary carcinoma
The following are treatment options for pituitary carcinoma. Your healthcare team will suggest treatments based on your needs and work with you to develop a treatment plan.
Since pituitary carcinoma is only diagnosed after it has spread to another part of the body (metastasized), treatments are usually to control the symptoms of the disease rather than to treat the disease itself (palliative treatment). Find out more about choosing care and treatment for advanced cancer.
Surgery is usually offered for pituitary carcinoma. The tumour in the pituitary gland is removed by transsphenoidal surgery or craniotomy.
If pituitary carcinoma spreads to the
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Dopamine agonists or somatostatin analogues are used if the pituitary carcinoma is a functioning tumour that makes too many hormones. Dopamine agonists are used for prolactin-producing tumours. Somatostatin analogues are used for pituitary carcinomas that make too much growth hormone, thyroid-stimulating hormone (TSH) or adrenocorticotropic hormone (ACTH).
Chemotherapy using temozolomide (Temodal) may be used to treat pituitary carcinoma. It is not a standard treatment, but some studies have shown promise using temozolomide.
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External beam radiation therapy may be offered after surgery for pituitary carcinoma. How many sessions of external beam radiation therapy are used depends on many factors including the size, location and number of metastases being treated, the specific type of radiation therapy used and how severe symptoms are.
Peptide receptor radionuclide therapy (PRRT) is rarely used for pituitary carcinoma. It is usually only available through a clinical trial.
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American Cancer Society. Treating Pituitary Tumors. 2014: https://www.cancer.org/cancer/pituitary-tumors/treating.html.
Asa SL, Mete O . The pituitary gland. Mete O, Asa SL (eds.). Endocrine Pathology. United Kingdom: Cambridge University Press; 2016: 12:315-397.
National Cancer Institute. Pituitary Tumors Treatment (PDQ®) Patient Version. 2016: https://www.cancer.gov/types/pituitary/patient/pituitary-treatment-pdq.
National Cancer Institute. Pituitary Tumors Treatment (PDQ®) Health Professional Version. 2016: https://www.cancer.gov/types/pituitary/hp/pituitary-treatment-pdq.