Treatments for stage 2 stomach cancer
Surgery is one of the main treatments for stage 2 stomach cancer.
A gastrectomy to remove all or part of the stomach is the most common type of surgery to treat stage 2 stomach cancer.
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A lymph node dissection is done to remove lymph nodes around the stomach for stage 2 stomach cancer.
Chemotherapy is a main treatment for stage 2 stomach cancer. Chemotherapy may be given before (neoadjuvant therapy) or after surgery (adjuvant therapy) or both before and after surgery (perioperative chemotherapy). It may also be given over the same time period as radiation therapy (called chemoradiation). The most common combinations of chemotherapy drugs given for stage 2 stomach cancer are:
- 5-fluorouracil (Adrucil, 5-FU) and leucovorin (folonic acid)
- ECF – epirubicin (Pharmorubicin), cisplatin (Platinol AQ) and 5-fluorouracil
- ECX – epirubicin, cisplatin and capecitabine (Xeloda)
- cisplatin and 5-fluorouracil
- paclitaxel (Taxol) and carboplatin (Paraplatin)
Radiation therapy may be offered for stage 2 stomach cancer along with chemotherapy. The type of radiation therapy used most often is external beam radiation therapy.
Alberta Health Services. Gastric Cancer. Alberta Health Services; 2013.
American Cancer Society. Stomach Cancer. Atlanta, GA: American Cancer Society; 2014: http://www.cancer.org/acs/groups/cid/documents/webcontent/003141-pdf.pdf.
Avital, I. et al . Cancer of the stomach. DeVita VT Jr, Lawrence TS, & Rosenberg SA. Cancer: Principles & Practice of Oncology. 9th ed. Philadelphia: Wolters Kluwer Health/Lippincott Williams & Wilkins; 2011: 80: pp. 924-954.
BC Cancer Agency (BCCA). Stomach Cancer Management Guidelines. BC Cancer Agency; 2013: http://www.bccancer.bc.ca/HPI/CancerManagementGuidelines/Gastrointestinal/02.Stomach/default.htm.
Knight G, Earle CC, Cosby R, et al . Neoadjuvant or Adjuvant Therapy for Resectable Gastric Cancer. Cancer Care Ontario. Evidence-Based Series (EBS) and Practice Guidelines (PG). Toronto, ON: Cancer Care Ontario; 2013.
National Cancer Institute. Gastric Cancer Treatment (PDQ®) Patient Version. Bethesda, MD: National Cancer Institute; 2014.
National Cancer Institute. Gastric Cancer Treatment (PDQ®) Health Professional Version. Bethesda, MD: National Cancer Institute; 2014.
National Comprehensive Cancer Network. Gastric Cancer (Version 1.2014). National Comprehensive Cancer Network; 2014.