Treatments for acute myelogenous leukemia
If you have acute myelogenous leukemia (AML), your healthcare team will create a treatment plan just for you. It will be based on your needs and may include a combination of different treatments. When deciding which treatments to offer for AML, your healthcare team will consider:
- your age
- the subtype of AML
- chromosome changes, or abnormalities
- whether you have had chemotherapy in the past to treat a different cancer
- whether you have had a blood disorder such as a myelodysplastic syndrome (MDS)
- whether the cancer has spread to the brain and spinal cord (called the central nervous system, or CNS)
- your overall health
Response to treatment @(Model.HeadingTag)>
How well leukemia responds to treatment is an important factor. It helps doctors determine prognostic risk group and plan future care. The goal of treatment is to reach a complete remission.
Complete remission, or complete response, means that the numbers of blood cells (red blood cells, white blood cells and platelets) have returned to normal levels and less than 5% of cells in the bone marrow are immature blood cells (called blast cells, or blasts). There are no general signs or symptoms of AML and no signs or symptoms that AML has spread to the brain and spinal cord (called the central nervous system, or CNS) or anywhere else in the body.
Minimal residual disease (MRD) means that there are blast cells in the bone marrow, but they can only be seen using very sensitive tests, such as flow cytometry or polymerase chain reaction (PCR). The blast cells can’t be seen with standard tests, such as looking at the cells under a microscope.
Active disease means that there are blast cells still present during treatment or the disease comes back (relapses) after treatment. Active disease means that more than 5% of cells in the bone marrow are blast cells.
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