Survival statistics for acute myelogenous leukemia
Survival statistics for acute myelogenous leukemia (AML) are very general estimates and must be interpreted very carefully. Because these statistics are based on the experience of groups of people, they cannot be used to predict a particular person’s chances of survival.
There are many different ways to measure and report cancer survival statistics. Your doctor can explain the statistics for AML and what they mean to you.
Net survival @(Model.HeadingTag)>
Net survival represents the probability of surviving cancer in the absence of other causes of death. It is used to give an estimate of the percentage of people who will survive their cancer.
In Canada, the 5-year net survival for AML is 21%. This means that about 21% of people diagnosed with AML will survive for at least 5 years.
Overall survival for AML @(Model.HeadingTag)>
People with AML must be treated. Without treatment, survival is usually measured in days to weeks.
With current treatment regimens, 65%–70% of people with AML reach a complete remission (which means that leukemia cells cannot be seen in the bone marrow) after induction therapy. People over the age of 60 usually have a lower response rate. About 25%–40% of people over the age of 60 are expected to survive 3 years or more.
If an allogeneic stem cell transplant is done during first remission, the 5-year disease-free survival rate is 30%–50%. If there has been no recurrence at 2 years after the stem cell transplant, the person has about an 80% chance of staying in complete remission for a long period of time.
People who had intensive consolidation therapy and those who had an allogeneic stem cell transplant have similar survival rates. The survival rates are slightly lower for people who have an autologous stem cell transplant.
Survival for acute promyelocytic leukemia @(Model.HeadingTag)>
The treatments offered and survival statistics for acute promyelocytic leukemia (APL) are different than for other types of AML. After reaching a complete remission, about 70%–90% of people with APL have long-term survival, and doctors consider them to be cured.
Questions about survival @(Model.HeadingTag)>
If you have AML, talk to your doctor about your prognosis. Prognosis depends on many factors, including:
- your medical history
- type of cancer
- characteristics of the cancer
- treatments chosen
- response to treatment
Only a doctor familiar with these factors can put all of this information together with survival statistics to arrive at a prognosis.
American Cancer Society. Leukemia - Acute Myeloid (Myelogenous). Atlanta, GA: American Cancer Society; 2013: http://www.cancer.org/acs/groups/cid/documents/webcontent/003110-pdf.pdf.
Canadian Cancer Statistics Advisory Committee. Canadian Cancer Statistics 2019 . Toronto, ON : Canadian Cancer Society; 2019: https://www.cancer.ca/en/cancer-information/cancer-101/canadian-cancer-statistics/past-editions-canadian-cancer-statistics/.
Kebriaei P, Champlin R, de Lima M, et al . Management of acute leukemias. DeVita VT Jr, Lawrence TS, & Rosenberg SA. Cancer: Principles & Practice of Oncology. 9th ed. Philadelphia: Wolters Kluwer Health/Lippincott Williams & Wilkins; 2014: 131: pp. 1928-1954.
National Cancer Institute. Adult Acute Myeloid Leukemia Treatment (PDQ®) Health Professional Version. Bethesda, MD: National Cancer Institute; 2014: http://www.cancer.gov.
Wiernik PH . Diagnosis and treatment of adult acute myeloid leukemia other than acute promyelocytic leukemia. Wiernik PH, Goldman JM, Dutcher JP & Kyle RA (eds.). Neoplastic Diseases of the Blood. 5th ed. Springer; 2013: 22: pp. 375-401.